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Endometrial Osseous Metaplasia: A Retrospective Analysis and Systematic Review
Olimpia Gabrielli1,2, Giuliana Orlandi1,2, Paolo Toscano1,2
1Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.
Endometrial osseous metaplasia, a rare uterine condition, often affects women of reproductive age with a history of miscarriage. Early detection is crucial for managing infertility and menstrual disorders associated with this condition.
Area of Science:
- Reproductive Medicine
- Gynecologic Pathology
Background:
- Endometrial osseous metaplasia is the presence of heterotopic bone within the uterine lining.
- This rare condition can impact reproductive health.
Purpose of the Study:
- To analyze cases of endometrial osseous metaplasia.
- To review the existing literature on this condition.
Main Methods:
- A retrospective, monocentric analysis of 10 patient cases.
- A systematic literature review was conducted.
Main Results:
- Most patients (9/10) were of reproductive age.
- Common symptoms included infertility and menstrual cycle disorders.
- Variations in metaplasia size and uterine location were observed.
Conclusions:
- Endometrial osseous metaplasia is associated with infertility and recurrent miscarriages.
- It is vital to consider this diagnosis in infertile patients with a history of miscarriage.
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