Genomic Full-Length Sequence of the HLA-DRB1*14:84 Allele, Identified by PacBio Sequencing

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Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

Yu-Li Zhu1, Ying-Chun Wang1, Zhi-Hui Feng1

  • 1HLA Typing Laboratory, Institute of Transfusion Medicine, Qingdao Blood Center, Qingdao, Shandong, China.

HLA
|May 28, 2025
PubMed

Keywords:
HLA‐DRB1*14:84PacBio sequencinggenomic full length

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...