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Copper-Induced Supramolecular Assemblies for Biomedical Applications.

Xingyao Sun1, Xiangyang Zhang1, Ziqi Zhao1

  • 1State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, P. R. China.

Chemmedchem
|May 28, 2025
PubMed
Summary
This summary is machine-generated.

Copper

Keywords:
copperenzymespeptidesself‐assemblies

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Area of Science:

  • Biochemistry and Materials Science

Background:

  • Copper is vital in biological systems, acting as an enzyme cofactor.
  • Excess copper triggers cuproptosis, a cell death linked to mitochondrial dysfunction.

Purpose of the Study:

  • To explore design principles of copper-induced self-assembly.
  • To review biomedical applications of these assemblies.

Main Methods:

  • Conceptual review of small molecules, peptides, and polymers.
  • Analysis of copper's chemical and biological properties.

Main Results:

  • Copper's properties enable supramolecular self-assembly.
  • These assemblies show potential in catalysis and therapeutics.

Conclusions:

  • Copper-induced self-assembly offers promising biomedical applications.
  • Further research is needed to address challenges and explore future directions.