Related Experiment Video
Updated: Jan 18, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Geriatric ocular trauma and mortality: A retrospective cohort study
Vincent Q Pham1, Hannah M Miller2, Elise O Fernandez2
1Northeast Ohio Medical University, Rootstown, Ohio, United States of America.
Purpose:
The objective of this investigation is to evaluate the 5-year mortality of geriatric patients who have sustained eye injuries.
Design:
This retrospective cohort study included patients aged 65 years or older who had histories of either ocular trauma or age-related nuclear cataracts. Subjects and controls: Patients with ocular trauma constituted the study group, while those with a history of cataracts served as controls.
Methods:
Data from the I2B2 Carolina Data Warehouse were analyzed. Patient demographics were collected, and the outcomes of interest were the overall mortality rate and annual mortality rates over a 5-year period. Chi-squared tests were utilized for the comparison of mortality data.
Main Outcomes And Measures:
The primary outcomes were overall mortality rates and annual mortality rates expressed as percentages.
Results:
The study group consisted of 602 patients who had suffered ocular trauma. The control group included 1066 patients of similar age who had been diagnosed with age-related nuclear cataracts at some point in their lives. Among the study group, 74 patients died within 5 years, while 69 patients in the control group died within the same timeframe, resulting in a study group mortality rate of 11.30% and a control group mortality rate of 6.47%. For patients with ocular trauma, the annual mortality rates were 4.15%, 2.60%, 1.96%, 2.54%, and 0.56%, respectively. For the control group, the annual mortality rates were 1.03%, 1.70%, 1.64%, 0.88%, and 1.38% respectively.
Conclusion:
The study suggests that geriatric patients who have experienced ocular trauma are at a higher risk of mortality compared to age-matched controls without such injuries. These findings highlight the necessity of identifying the causes of geriatric periorbital trauma and underscore the importance of close patient follow-up to improve outcomes.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment

