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Related Experiment Video

Updated: Jun 10, 2026

Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

Published on: February 12, 2018

Associations between age at natural menopause and risk of hypothyroidism among postmenopausal women from the Canadian

Durmalouk Kesibi¹, Michael Rotondi¹, Heather Edgell¹

¹School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada.

|May 28, 2025

Summary

This study found no significant link between the age women experience natural menopause and their risk of developing hypothyroidism. Understanding menopause timing is crucial for women

Related Experiment Videos

Last Updated: Jun 10, 2026

Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice

Published on: February 12, 2018

Area of Science:

Endocrinology
Reproductive Health
Gerontology

Background:

Menopause involves significant physiological changes in women.
Early menopausal age is associated with adverse health outcomes.
Estrogen's effect on hypothyroidism requires further investigation.

Purpose of the Study:

To investigate the association between age at natural menopause and the incidence of hypothyroidism.
Focus on postmenopausal Canadian women using longitudinal data.

Main Methods:

Analysis of data from the Canadian Longitudinal Study on Aging over 10 years.
Survival analysis to determine time to hypothyroidism onset.
Multivariable Cox regression models to assess the relationship between menopausal age and hypothyroidism risk.

Main Results:

No significant association was found between age at natural menopause and the risk of developing hypothyroidism.
Analysis included women without pre-existing hypothyroidism.

Conclusions:

Age at natural menopause does not appear to be a significant risk factor for hypothyroidism in postmenopausal women.
Further research may explore other factors influencing hypothyroidism incidence.