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Updated: Jun 14, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Does ACR TI-RADS increase efficacy of thyroid ultrasounds?
S J C van der Burg1, M J Van Rietschoten1, N A 't Hart2
1Department of Surgery, Isala clinics, Dokter van Heesweg 2, 8025 AB Zwolle, the Netherlands.
Background:
The American College of Radiology Thyroid Imaging Results and Data System (ACR TI-RADS) is a risk stratification system (RSS) to assess ultrasounds of thyroid nodules. This study aims to evaluate if the implementation of ACR TI-RADS reduces fine needle aspiration cytology (FNAC) of benign nodules.
Material & Methods:
All patients diagnosed with a thyroid nodule, and who received an ultrasound between January 2018 and February 2020 were included. Period I included patients undergoing ultrasound before implementation of ACR TI-RADS and period II after implementation. The impact of ACR TI-RADS on the number of FNACs with the accompanying cytological results and guideline concordance were analyzed.
Results:
In this study, 787 patients and 889 ultrasounds were included. Of these ultrasounds, 403 were performed in period I and 486 in period II. The proportion of ultrasounds leading to FNAC decreased significantly since implementation (51.6 % vs. 43.6 %, p = 0.018) while the proportion of benign cytology results decreased significantly as well (84.4 % vs. 73.6 %, p = 0.020). Furthermore, since ACR TI-RADS implementation, physicians followed the accompanying guidelines on follow-up in 70.4 % of the cases.
Conclusion:
A decrease of FNAC of benign thyroid nodules was observed since implementation of ACR TI-RADS and this RSS was easily implemented in our clinic.
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