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External Quality Assessment in Diagnostic Cytopathology: Current Programs, Challenges, and Perspectives
Irena Srebotnik Kirbis1, Margareta Strojan Fležar2
1Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia, irena.srebotnik-kirbis@mf.uni-lj.si.
Acta Cytologica
|May 28, 2025
Summary
External quality assessment (EQA) and proficiency testing (PT) are crucial for laboratory quality. This review finds significant gaps in current EQA/PT programs for non-gynecological cytopathology, especially in Europe.
Area of Science:
- Medical Diagnostics
- Laboratory Medicine
- Pathology
Background:
- External quality assessment (EQA) and proficiency testing (PT) are essential for laboratory quality management.
- These are key requirements for diagnostic laboratory accreditation.
Purpose of the Study:
- To review the current state of EQA/PT programs in diagnostic cytopathology.
- To identify gaps in comprehensive EQA/PT for non-gynecological samples.
Main Methods:
- Literature review of existing EQA/PT programs.
- Analysis of program scope and coverage in diagnostic cytopathology.
Main Results:
- Current EQA/PT programs are largely regional or national.
- Existing programs only partially cover the cytodiagnostic examination process.
Conclusions:
- Significant gaps exist in comprehensive EQA/PT for diagnostic non-gynecological cytopathology, particularly in Europe.
- Challenges include sample limitations, varied lab procedures, biomarker testing, and subjective reporting, requiring adapted EQA approaches.
