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Related Experiment Video

Updated: Jul 30, 2026

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

3D Microtissues for Injectable Regenerative Therapy and High-throughput Drug Screening

Published on: October 4, 2017

Microgels: from synthesis to tissue regeneration applications.

Sung Yun Hann^1,2,3, Yunsung Kang^1,3, Haitao Cui^4,5

¹Department of Precision Mechanical Engineering, Kyungpook National University, Sangju 37224, Republic of Korea.

|May 28, 2025

Summary

Microgels are versatile hydrogels for tissue engineering and regenerative medicine. Advanced fabrication and 3D bioprinting enhance their use in creating functional tissue constructs and therapies.

Keywords:

3D bioprinting assembly cell encapsulation injectable hydrogels tissue regeneration

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Area of Science:

Biomaterials Science
Tissue Engineering
Regenerative Medicine

Background:

Microgels offer unique properties for mimicking extracellular matrix.
They are biocompatible, controllable, and injectable hydrogel platforms.
Their modularity suits diverse tissue engineering needs.

Purpose of the Study:

To review microgel fabrication methods.
To highlight microgels' roles in cell encapsulation, therapy delivery, and tissue development.
To discuss advanced strategies and future potential.

Main Methods:

Systematic review of microgel fabrication techniques.
Exploration of advanced strategies like injectable hydrogels and assembled microgel platforms.
Analysis of 3D bioprinting applications for scaffold generation.

Main Results:

Advanced strategies enable customizable and functional tissue constructs.
3D bioprinting facilitates patient-specific scaffolds with high cellular viability.
Stimuli-responsive and 4D microgels offer dynamic, tunable microenvironments.

Conclusions:

Microgels are crucial for developing multifunctional tissue products.
Efficient mass production and customization are key for clinical translation.
Innovations will accelerate the integration of microgel-based therapies.