Related Experiment Video
Updated: Sep 20, 2025

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Symphony of crossfire: Aneurysm, dual vessel occlusion, and lymphoma's hypercoagulable crescendo a case report
Said Al-Najjar1, Noor Abu Hantash2, Dana Bader3
1Cardiology Department, Al-Bashir Hospital, Jordan.
Insights
Diagnosing occult myocardial infarction in complex cancer patients is challenging. Multimodal imaging and intervention were crucial for identifying and treating coronary occlusions and a left ventricular aneurysm in a lymphoma patient.
Area of Science:
- Cardiology
- Oncology
- Diagnostic Imaging
Background:
- Occult myocardial infarction can present atypically in patients with malignancy, advanced age, and comorbidities.
- Diagnosing recurrent infarction is complicated by these atypical presentations.
Purpose of the Study:
- To present a complex case of occult myocardial infarction in a patient with lymphoma and comorbidities.
- To highlight the diagnostic challenges and successful management strategies.
Main Methods:
- Concurrent percutaneous coronary intervention (PCI) and echocardiography were used for diagnosis.
- Retrograde imaging identified a left ventricular aneurysm.
- Stent placement in affected coronary arteries.
Main Results:
- Thrombotic occlusions in two coronary vessels were identified and treated with PCI.
- Acute occlusions were resolved by empirical stenting.
- A previously undiagnosed anteroapical left ventricular aneurysm was revealed.
Conclusions:
- Multimodal imaging is essential for diagnosing cardiovascular events in oncological patients with atypical presentations.
- Integrated diagnostic and interventional approaches are vital for complex cases.
Abstract:
Occult asymptomatic myocardial infarction in patients with malignancy (lymphoma), advanced age, and multiple comorbidities may present atypically, complicating the diagnosis of presumed recurrent infarction. We present a highly complex case of a 66-year-old male with lymphoma and multiple comorbidities who collapsed with diffuse ST-segment elevation on electrocardiography (ECG). The diagnostic challenge required concurrent percutaneous coronary intervention (PCI) and echocardiography to identify the thrombotic occlusions in two coronary vessels. Empirical placement of stents in the right coronary artery and left circumflex artery resolved the acute occlusions, while retrograde imaging revealed a previously undiagnosed anteroapical left ventricular aneurysm. This case underscores the importance of integrating multimodal imaging in oncological patients with atypical cardiovascular presentations.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis I: Introduction
Aneurysm III: Interprofessional Care

