Related Experiment Video
Updated: Jan 18, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Steroid-responsive Encephalopathy with a Primary CMV Infection Complicated by Enteritis in a Young Woman with
Ryosuke Oka1, Hajime Yoshimura1, Shigeo Hara2
1Department of Neurology, Kobe City Medical Center General Hospital, Japan.
Abstract:
A 23-year-old woman with ulcerative colitis (UC) presented with fever, headache, an altered mental status, and bloody stool. A neurological examination, magnetic resonance imaging, and electroencephalography revealed right-side dominant encephalopathy. Although a serological analysis revealed a primary cytomegalovirus (CMV) infection, the cerebrospinal fluid (CSF) showed no evidence of a viral load, although the CSF interleukin-6 levels were markedly elevated (1,670 pg/mL). Encephalopathy rapidly improved with steroid therapy; however, the presence of bloody stool persisted. A colon biopsy revealed concurrent CMV enteritis, which improved with ganciclovir. This case shows that steroid-responsive encephalopathy can occur during a primary CMV infection. Additionally, CMV enteritis complicated by a primary CMV infection should be considered in patients with UC.
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Drugs for Treatment of Ulcerative Colitis in IBD
Chronic Pancreatitis II: Collaborative Care
Assessment:

