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A Systematic Review of Follicular Unit Graft Survival Rates After Hair Transplantation in Primary Cicatricial
Valerie Yii1, Anthony Moussa1, Daranporn Triwongwaranat1,2
1Sinclair Dermatology Investigational Research Education and Clinical Trials (DIRECT), East Melbourne, Vic., Australia.
Background:
Primary cicatricial alopecia (PCA) refers to a clinically diverse group of inflammatory hair loss disorders characterized by the irreversible destruction and scarring of hair follicles. Hair transplantation (follicular unit extraction [FUE] or strip harvesting follicular unit transplantation [FUT]) has been proposed as a treatment for inactive PCA.
Objective:
This study aims to evaluate the efficacy and safety of HT for the management of PCA.
Methods:
A systematic review was conducted to identify studies assessing treatment of PCA in adults (≥18 years) with FUE or FUT. The primary outcome measure was follicular unit (FU) graft survival rate. Secondary outcomes included postoperative complications and patient satisfaction.
Results:
Eight observational studies with a total of 123 patients met the inclusion criteria. Overall, the weighted FU graft survival rate after HT was 82.7% at 7 to 12 months, 73.3% at 13 to 24 months, 58.4% at 25 to 36 months, 55.4% at 37 to 48 months and 39.6% at 49 to 72 months. Four patients developed reactivation of their disease after HT.
Conclusion:
The FU graft survival rate after FUE or FUT for the management of inactive PCA peaks at 1 year and diminishes over time.
