Cognitive, affective and behavioral functioning in patients with olfactory groove meningiomas: a systematic review
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View abstract on PubMed
Summary
This summary is machine-generated.Olfactory groove meningiomas (OGMs) frequently cause cognitive and behavioral issues. While some recovery is possible after surgery, larger tumors and specific approaches may hinder progress, necessitating further research.
Area Of Science
- Neuroscience
- Neurosurgery
- Psychiatry
Background
- Olfactory groove meningiomas (OGMs) are associated with cognitive, affective, and behavioral deficits.
- These symptoms in OGM patients are not well understood.
- Understanding these deficits is crucial for improving patient outcomes.
Purpose Of The Study
- To systematically review the prevalence, nature, and postoperative outcomes of cognitive, affective, and behavioral deficits in OGM patients.
- To identify factors influencing neuropsychological recovery.
- To guide future treatment strategies for OGM patients.
Main Methods
- A systematic review was conducted following PRISMA guidelines, searching PubMed, Google Scholar, and ScienceDirect.
- Studies reporting cognitive, affective, or behavioral symptoms in OGM patients were included.
- Data extraction and risk of bias assessment were performed by two independent reviewers.
Main Results
- 38 studies met inclusion criteria, revealing high prevalence of psychiatric symptoms (14-100%) in OGM patients.
- Common deficits include memory and attention problems, confusion, disorientation, depression, apathy, and behavioral changes.
- Postoperative improvements in Mini-Mental State Examination (MMSE) scores suggest cognitive recovery, influenced by tumor size and surgical approach.
Conclusions
- Cognitive, affective, and behavioral deficits are common in OGM patients but often underdiagnosed.
- Limited use of standardized assessments and small sample sizes necessitate more rigorous research.
- Future research should focus on multicenter collaborations, prospective designs, and validated tools to optimize OGM patient care.
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