Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-term Depression01:05

Long-term Depression

33.2K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.2K
Long-term Depression01:03

Long-term Depression

3.1K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.1K
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

681
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
681
Depression: Overview01:18

Depression: Overview

800
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
800

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Multi-lead electrocardiogram atrial fibrillation detection algorithm based on multi-scale patch-based attention].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi·2026
Same author

Risk factors and a prediction model of poor prognosis in patients with invasive aspergillosis in a general hospital.

BMC infectious diseases·2026
Same author

A feasibility study on inferring connectivity changes in frontal lobes of MDD patients via spectral DCM.

Brain informatics·2026
Same author

Enhanced vertebrae localization in CT volumes: a two-stage deep learning framework.

BMC medical imaging·2026
Same author

A rare case report of primary intraosseous meningioma with anaplastic histology.

Discover oncology·2026
Same author

Interlayer-aware postoperative facial appearance prediction in orthognathic surgery with bio-geometric guidance.

Physics in medicine and biology·2026
Same journal

Multimodal Contrastive Spatiotemporal Self-Organizing Neural Networks for In-Home Activity Learning of Mild Cognitive Impairment.

IEEE journal of biomedical and health informatics·2026
Same journal

Integrating Multi-View Residue Graph and Protein Language Model for Cell-Penetrating Peptide Prediction via Global-Local Graph Aggregation and Cross-Attentive Fusion.

IEEE journal of biomedical and health informatics·2026
Same journal

An Ultra-Lightweight Cross-scale Attention Mamba Network for Accurate Skin Lesion Segmentation.

IEEE journal of biomedical and health informatics·2026
Same journal

Explanation-Guided Reconstruction of Missing Clinical Features for Survival Prediction in Pancreatic Cancer.

IEEE journal of biomedical and health informatics·2026
Same journal

stDGCN: A dual-augmentation graph convolutional network for identifying spatial domains with attention mechanism.

IEEE journal of biomedical and health informatics·2026
Same journal

Patient-specific Biomechanical Investigation of Percutaneous Pulmonary Valves: Towards the Integration of Routinely Acquired Clinical Data and Fluid-structure Interaction Simulations.

IEEE journal of biomedical and health informatics·2026
See all related articles

Related Experiment Video

Updated: Jan 18, 2026

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
05:19

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Published on: July 7, 2023

3.3K

TTFNet: Temporal-Frequency Features Fusion Network for Speech Based Automatic Depression Recognition and Assessment.

Xiyuan Chen, Zhuhong Shao, Yinan Jiang

    IEEE Journal of Biomedical and Health Informatics
    |May 29, 2025
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces TTFNet, a novel deep learning method for automatic depression detection using hybrid speech features. TTFNet enhances early screening by analyzing both temporal and frequency domain speech characteristics.

    More Related Videos

    Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
    07:12

    Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

    Published on: August 2, 2021

    4.1K
    Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
    06:04

    Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

    Published on: January 17, 2025

    1.3K

    Related Experiment Videos

    Last Updated: Jan 18, 2026

    Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
    05:19

    Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

    Published on: July 7, 2023

    3.3K
    Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
    07:12

    Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

    Published on: August 2, 2021

    4.1K
    Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
    06:04

    Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

    Published on: January 17, 2025

    1.3K

    Area of Science:

    • Computational linguistics
    • Psychiatry
    • Machine learning

    Background:

    • Depression diagnosis lacks objective, convenient early screening methods.
    • Phonological differences exist between depressed patients and healthy individuals.

    Purpose of the Study:

    • To propose an automatic depression detection method using hybrid speech features.
    • To enhance early depression screening through advanced deep learning techniques.

    Main Methods:

    • Developed TTFNet, a deep learning model utilizing hybrid speech features.
    • Employed quaternion representation for frequency domain features (log-Mel spectrogram).
    • Integrated quaternion VisionLSTM and sLSTM with wav2vec 2.0 for temporal features.
    • Utilized an XConformer block and dual-path fusion for feature complementarity.

    Main Results:

    • TTFNet outperforms current state-of-the-art methods on multiple datasets (AVEC 2013, AVEC 2014, DAIC-WOZ, E-DAIC).
    • Achieved superior performance in both depression recognition and severity prediction tasks.

    Conclusions:

    • The proposed TTFNet method offers a promising approach for objective and convenient depression screening.
    • Hybrid speech features and advanced deep learning architectures significantly improve depression detection accuracy.