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Interferon-γ Therapy in Patients With Refractory Disseminated Coccidioidomycosis
Chen Wang1, Brenna A LaBere2, Michell M Lozano Chinga2
1Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
None:
Refractory disseminated coccidioidomycosis (DCM) is a severe disease with limited treatment options. This report reviews our own and prior published experiences using adjunctive interferon-γ therapy in refractory DCM, showing overall favorable responses in patients without signal transducer and activator of transcription 1 gain-of-function mutations.
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