Clinical evaluation of some phosphorus bone-imaging agents: concise communication

Four different Tc-99m labeled phosphorus-based bone-imaging agents were compared by a scan-evaluation technique in which the skeletal uptake was visually assessed at selected sites. A detailed statisticalanalysis of scans, by each of three independent evaluators, on a total of 140 different patients showed that two of the agents (based on pyro- and on trimetaphosphate) were superior. The statistical analysis showed good agreement between the investigators and consistency in thier repeat evaluations.