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Childhood Humoral Immunity During and After COVID-19 Lockdowns
Coralie Mallebranche1, Emeline Vinatier2, Julien Lejeune3
1From the University of Angers, Université de Nantes, Inserm, CNRS, CRCI2NA, SFR ICAT, CHU Angers, Pediatric Immuno-hemato-oncology Unit, Angers, France.
None:
Our study, including serum from 3678 hospital inpatients and outpatients sampled before, during and after the COVID-19 lockdown periods, showed a significant decrease in overall IgG levels during the periods of sanitary restriction, particularly in children 3-10 years of age. Few months after the lifting of COVID-19 restrictions, immunoglobulin levels normalized. COVID-19 lockdowns may have induced a transient humoral immune gap.
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