Predicting Contrast-Induced Acute Kidney Injury in ST-Segment Elevation Myocardial Infarction Patients Undergoing
Yeliz Guler1, Abdullah Yildirim2, Onur K Uysal2
1Department of Cardiology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Heart, Lung & Circulation
|May 29, 2025
Summary
The albumin-bilirubin (ALBI) score can predict contrast-induced acute kidney injury (CI-AKI) in ST-segment elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PCI). This simple tool aids in identifying high-risk individuals for CI-AKI.
Area of Science:
- Cardiology
- Nephrology
- Biomarkers
Background:
- Contrast-induced acute kidney injury (CI-AKI) is a major complication in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI).
- Predictive tools for CI-AKI are crucial for risk stratification and management in this population.
Purpose of the Study:
- To assess the predictive capability of the albumin-bilirubin (ALBI) score for CI-AKI.
- To evaluate the ALBI score's utility in STEMI patients undergoing primary PCI.
Main Methods:
- Retrospective analysis of 2,011 STEMI patients who underwent primary PCI.
- Exclusion of patients with severe renal or liver disease.
- Statistical analysis including receiver-operating characteristic (ROC) and logistic regression.
Main Results:
- CI-AKI developed in 9.1% of the study cohort.
- Higher ALBI scores were significantly associated with increased CI-AKI risk.
- An ALBI score > -2.54 predicted CI-AKI with 70% sensitivity and 61.5% specificity; it was an independent predictor (OR 9.731, p<0.001).
Conclusions:
- The ALBI score is a simple, cost-effective predictor of CI-AKI in STEMI patients undergoing PCI.
- Clinical integration of the ALBI score may improve CI-AKI prediction and management.
- Further research is needed to validate findings and elucidate mechanisms.
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