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Related Experiment Videos

Mitral valve prolapse. Quantitative analysis and long-term follow-up.

Z Vered, S Oren, B Rabinowitz

    Israel Journal of Medical Sciences
    |August 1, 1985
    PubMed
    Summary

    This study introduces a new echocardiogram method to measure mitral valve prolapse (MVP) degree. While MVP measurements and left atrial size increased over time, no correlation was found with clinical symptoms or complications.

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    Area of Science:

    • Cardiology
    • Echocardiography
    • Valvular Heart Disease

    Background:

    • Systolic posterior motion of the mitral valve is a key echocardiographic finding.
    • Mitral valve prolapse (MVP) requires accurate quantification for clinical assessment.
    • Longitudinal studies are crucial for understanding the progression of valvular heart disease.

    Purpose of the Study:

    • To present a novel method for quantifying the degree of mitral valve prolapse (MVP) using M-mode echocardiography.
    • To evaluate the correlation between the degree of MVP and clinical parameters, ECG findings, and complications.
    • To assess the progression of MVP and left atrial size over time.

    Main Methods:

    • A cohort of 42 patients with systolic posterior motion of the mitral valve was reevaluated.

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  • A new method involving lines A and B was developed to measure the degree of MVP.
  • Clinical and echocardiographic parameters, including left atrial size, were assessed over mean follow-up periods of 6.7 and 5.1 years, respectively.

    • Main Results:

    • The mean degree of MVP increased significantly from 5.9 +/- 2.1 mm to 7.1 +/- 2.9 mm (P < 0.01).
    • Mean left atrial size also increased significantly from 3.0 +/- 0.5 cm to 3.5 +/- 0.8 cm (P < 0.01).
    • No significant correlation was found between the degree of MVP and symptoms, auscultatory findings, or the presence of complications.

    Conclusions:

    • The novel M-mode echocardiography method allows for reliable measurement of the degree of MVP.
    • The degree of MVP and left atrial size appear to increase over time, suggesting a progressive nature of the condition.
    • Complications such as endocarditis and transient ischemic attacks occurred in a notable proportion of patients, despite the absence of a direct correlation with MVP severity.