Identification authenticity Tibet snow tea of Lichen Thamnolia spp. using untargeted, pseudotargeted metabolomics and
Ying Ye1, Jiao Zhang2, Tao Lin2
1Institute of Quality Standards and Testing Technology, Yunnan Academy of Agricultural Sciences, Agricultural Product Quality Supervision and Inspection Center, Ministry of Agriculture, Kunming, Yunnan 650223, China; School of Chemical Science and Technology, Yunnan University, Kunming 650000, China.
Abstract:
A method was developed to authenticate Tibet snow tea (Lichen Thamnolia spp.) by UV fluorescence and high resolution mass spectrometry with chemometrics analysis. The representative snow teas were collected from Shannan in Tibet Autonomous Region. Tibet snow teas can be discriminated by the high resolution mass spectrometry (HRMS) with statistical methods. Total flavonoids were founded including 4 mono-nuclear phenols, 3 depsides and 3 depsidones. There was a good correlation between the antioxidant activity and the total phenols and total flavonoids, as indicated by the correlation coefficient. Three biomarkers were semi-quantitatively analyzed by targeted metabolomics and presumed to interact with Alzheimer's disease through molecular docking, suggesting that they are the primary active components of Tibet snow tea in treating Alzheimer's disease.
More Related Videos
09:24Standardized Identification of Compound Structure in Tibetan Medicine Using Ion Trap Mass Spectrometry and Multiple-Stage Fragmentation Analysis
Published on: March 17, 2023
04:22Author Spotlight: Exploring Sex-Specific Glial Signatures and Therapeutic Leads for Alzheimer's Disease
Published on: May 20, 2024
