Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

2
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
2
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

2
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
2
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

2
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
2
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

128
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
128
Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

3
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
3
Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

2
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
2

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of preoperative neoplasia and rectal cuff inflammation on initial pouchoscopy with subsequent neoplasia development in inflammatory bowel disease patients with an ileal pouch-anal anastomosis: a case-control study.

Inflammatory bowel diseases·2026
Same author

Preoperative anorectal manometry is associated with cuffitis but not proximal pouch inflammation after IPAA creation.

Inflammatory bowel diseases·2026
Same author

Urinary Fungal Microbiome and Associations With Overactive Bladder, Antibiotics and Therapy Response.

Neurourology and urodynamics·2026
Same author

Urinary Microbiome and Metabolome Differentiate Overactive Bladder From the Physiological State, and Reflect Recent Antibiotic Use and Treatment Response.

The Journal of urology·2026
Same author

Editorial Comment on "Variability in Cystatin C- and Creatinine-estimated Glomerular Filtration Rate in Adults With Spina Bifida".

Urology·2026
Same author

How Could the Proposed International Continence Society (ICS) Global Urodynamics Data Repository (GUDRep) Demonstrate the Clinical Role and Cost Effectiveness of Urodynamics in Individual Patients? ICI-RS 2025.

Neurourology and urodynamics·2025

Related Experiment Video

Updated: Jun 12, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.1K

Fecal Microbiota Transplant Is Associated With Resolution of Recurrent Urinary Tract Infection.

Stacy H Jeong1, Sandip P Vasavada1, Bret Lashner2

  • 1Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.

Urology
|May 30, 2025
PubMed
Summary

Fecal microbiota transplant (FMT) therapy, used for recurrent C. difficile colitis, significantly reduced recurrent urinary tract infections (rUTIs) in a small patient group. This suggests gut microbiome modulation may help prevent rUTIs.

More Related Videos

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.8K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

3.9K

Related Experiment Videos

Last Updated: Jun 12, 2025

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
07:06

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

Published on: December 8, 2014

27.1K
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
05:41

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model

Published on: April 6, 2022

2.8K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

3.9K

Area of Science:

  • Microbiology
  • Gastroenterology
  • Urology

Background:

  • Recurrent urinary tract infections (rUTIs) significantly impact quality of life.
  • Fecal microbiota transplant (FMT) is an effective treatment for recurrent Clostridoides difficile colitis.
  • The gut microbiome's role in urinary tract health is increasingly recognized.

Purpose of the Study:

  • To investigate the association between FMT and the resolution of rUTI.
  • To determine if FMT can reduce the frequency of UTIs in patients with a history of rUTI.

Main Methods:

  • Retrospective review of a prospectively accrued database of patients who underwent FMT for recurrent C. difficile colitis.
  • Patients with rUTI in the 2 years prior to FMT were identified.
  • UTI status and frequency before and after FMT were compared using statistical analysis (Wilcoxin matched pairs signed rank test).

Main Results:

  • None of the 11 patients with prior rUTI experienced recurrence after FMT (P = .001).
  • The average number of UTIs decreased from 3.7 in the 2 years pre-FMT to 0.27 in the 2 years post-FMT (P = .001).
  • Median time to UTI recurrence was 19.6 months.

Conclusions:

  • FMT was associated with the resolution of rUTI and a significant reduction in UTI frequency.
  • These findings support the hypothesis that gut microbiome modulation may reduce rUTI risk.
  • Further clinical trials are warranted to assess FMT's safety and efficacy for rUTI.