Adenomyosis and coexisting gynecologic pathologies: How often do they coexist?
Hale Goksever Celik1,2, Ipek Betul Ozcivit Erkan3, Elif Goknur Topcu4
1Department of Obstetrics and Gynecology, Faculty of Medicine, Acibadem University, Istanbul, Türkiye.
Summary
Adenomyosis frequently co-occurs with other gynecologic conditions, including uterine fibroids, endometrial polyps, and cancer. This study highlights the importance of considering these associations in diagnosis and treatment planning.
Area of Science:
- Gynecologic Oncology
- Reproductive Medicine
- Pathology
Background:
- Adenomyosis is a common benign gynecologic condition.
- It often coexists with other uterine pathologies, impacting patient management.
- Understanding these associations is crucial for accurate diagnosis and treatment.
Purpose of the Study:
- To investigate the prevalence and types of gynecologic pathologies accompanying adenomyosis.
- To compare clinical and demographic characteristics of patients with adenomyosis alone versus those with coexisting conditions.
- To identify risk factors and patterns associated with these comorbidities.
Main Methods:
- Multicenter retrospective cohort study of 1455 women undergoing hysterectomy.
- Classification into groups: adenomyosis only (n=102) vs. adenomyosis with other pathologies (n=1353).
- Analysis of demographic data, clinical characteristics, ultrasound findings, and pathology reports.
Main Results:
- The most common coexisting pathology was myoma uteri (43.3%), followed by cancer and endometrial polyps.
- Cancer was more prevalent in postmenopausal patients, particularly endometrial cancer (24.1% overall).
- Adenomyosis was more frequent in patients with menstrual irregularities compared to pelvic pain or postmenopausal bleeding.
Conclusions:
- Adenomyosis is frequently associated with myoma uteri, endometrial polyps, and endometrial cancer.
- The study underscores the need for comprehensive evaluation in patients diagnosed with adenomyosis.
- Further research into the etiological links between adenomyosis and these comorbidities is warranted.
Related Concept Videos
01:24Disorders of the Female Reproductive System
3.9K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.9K
02:07Oogenesis
69.1K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
69.1K
01:17Chronic Bowel Disorders: Introduction
748
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
748
01:16Uterine Tubes
2.1K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.1K
01:29Appendicitis-II: Diagnostic Studies and Management
525
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
525
01:26Ovaries
2.2K
The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of...
On the ovarian surface, a layer of...
2.2K