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Exercise-Induced Hypertension Is Associated With Gestational Hypertension Occurrence in Patients With Repaired Aortic
Carrie A Zografos1, Elena Wadden1, Catherine M Albright2
1Department of Medicine, University of Washington, Seattle, Washington, USA.
Exercise-induced hypertension (EIH) in patients with repaired aortic coarctation (rCoA) may predict the development of gestational hypertension (GHTN). This finding is crucial for managing high-risk pregnancies in this population.
Area of Science:
- Cardiology
- Obstetrics
- Hypertensive Disorders of Pregnancy
Background:
- Patients with repaired aortic coarctation (rCoA) face risks of exercise-induced hypertension (EIH) and gestational hypertension (GHTN).
- The predictive value of EIH for subsequent GHTN in rCoA patients with normal resting blood pressure (BP) remains unclear.
Purpose of the Study:
- To investigate the association between EIH and the occurrence of GHTN in rCoA patients with normal resting BP.
- To identify predictors of GHTN in this specific patient cohort.
Main Methods:
- Retrospective analysis of patients from a cardio-obstetrics clinic (2011-2023).
- Echocardiogram and cardiopulmonary exercise testing performed pre-pregnancy.
- BP monitored throughout pregnancy; echocardiogram during pregnancy.
- Statistical analysis included Pearson correlation and logistic regression.
Main Results:
- 31% of included rCoA patients developed GHTN during pregnancy.
- EIH was independently associated with a threefold increased risk of GHTN.
- Abnormal global longitudinal strain and lower peak oxygen consumption were noted in patients with GHTN.
Conclusions:
- EIH may serve as a significant predictor for GHTN development in patients with rCoA.
- Early identification of EIH could aid in risk stratification and management of pregnancy in rCoA patients.
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