Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

2.6K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

490
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
490
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

623
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
623
Asthma-I: Introduction01:29

Asthma-I: Introduction

2.8K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.8K
Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

407
Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
407
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

3.3K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combined large and small airway obstruction is associated with increased exacerbation frequency and poorer symptom control in persistent asthma.

The journal of allergy and clinical immunology. In practice·2026
Same author

Patients' perspectives of eosinophilic granulomatosis with polyangiitis within the context of a clinical trial.

EULAR rheumatology open·2026
Same author

Reply to Siddiqui et al., Godbout et al., and to Chang and Mao.

American journal of respiratory and critical care medicine·2026
Same author

Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma.

Allergy·2026
Same author

Efficacy and safety of tezepelumab versus placebo in reducing oral corticosteroid use in adults with severe, oral corticosteroid-dependent asthma (SUNRISE): a multicentre, placebo-controlled, double-blind, phase 3 trial.

The Lancet. Respiratory medicine·2026
Same author

Real-world outcomes and corticosteroid sparing with mepolizumab for EGPA or HES.

The journal of allergy and clinical immunology. Global·2026

Related Experiment Video

Updated: Sep 19, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K

Asthma therapeutics: Past, present, and future.

Sarah L Rhoads1, Lior Seluk1, Michael E Wechsler1

  • 1Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, Denver, Colorado.

Pharmacological Reviews
|May 31, 2025
PubMed
Summary

Asthma treatments have evolved from general therapies to targeted biologic medications. Novel approaches promise even more personalized medicine for millions suffering from this airway disease.

Area of Science:

  • Pulmonology and immunology
  • Pharmacology and drug discovery

Background:

  • Asthma, a chronic airway inflammatory disease affecting over 300 million globally, has seen treatment evolve significantly since its initial recognition.
  • Early 20th-century advancements introduced immunotherapy and inhaled corticosteroids, while the 21st century accelerated the development of novel pharmacotherapies.

Purpose of the Study:

  • To review the historical standard-of-care asthma treatment strategies.
  • To outline current asthma management recommendations.
  • To explore emerging novel therapies and future directions in personalized asthma medicine.

Main Methods:

  • Review of historical and current literature on asthma treatment paradigms.
  • Analysis of the impact of novel biologic therapies on asthma control.

More Related Videos

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

40.9K
A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

3.9K

Related Experiment Videos

Last Updated: Sep 19, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.0K
Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
07:28

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

Published on: April 6, 2017

40.9K
A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

3.9K
  • Discussion of emerging therapeutic targets and personalized medicine approaches.

    • Main Results:

    • Biologic therapies, including monoclonal antibodies targeting IgE, TSLP, IL-4, IL-5, and IL-13, have revolutionized severe asthma care.
    • These targeted treatments reduce exacerbations, lower oral corticosteroid doses, improve lung function, and enhance quality of life.
    • Despite advancements, current biologic therapies represent an early stage in personalized asthma management.

    Conclusions:

    • Asthma treatment has shifted from broad anti-inflammatory and bronchodilatory therapies to precisely targeted biologic agents.
    • Understanding asthma phenotypes and endotypes facilitates precision medicine, with monoclonal antibodies offering significant benefits for severe cases.
    • Future research promises further personalization of asthma treatment, improving outcomes and quality of life for a wider patient population.