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Asymmetric synthesis of potent and orally bioavailable thiophene-based EZH2 inhibitors

Xinrong Tian1, Ken Newlander1, Louis LaFrance1

  • 1GSK, Research and Development, 1250 South Collegeville Road, Collegeville, PA 19426, United States.

Bioorganic & Medicinal Chemistry Letters
|June 1, 2025
PubMed

Keywords:
EZH2Enantioselective hydrogenationInhibitorThiophene

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