tRNA modification in plant pathogenic fungi: roles, mechanisms, and implications for pathogenicity
Ziwei Lv1, Hong Hu1, Yinan Li2
1National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, China.
Abstract:
Transfer RNA (tRNA) modifications refer to the chemical alterations that occur on tRNA molecules, which are essential for their structure, stability, and function. These modifications have been shown to play crucial roles in diverse biological processes across different organisms. Recent studies have highlighted that specific tRNA modifications are directly linked to virulence traits and infection processes in plant pathogenic fungi. This review aims to explore their roles in fungal biology and pathogenicity, summarize the current understanding of the molecular mechanisms of tRNA modification in plant pathogenic fungi, and discuss the potential implications for developing novel antifungal strategies.
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