Benefit of Topical Haemocoagulase Solution Application in Tonsillectomy: A Double-Blinded Study

This study aims to evaluate the benefit of topical haemocoagulase application during tonsillectomy in diminishing the operation time and intraoperative blood loss, as well as postoperative healing effects.

A randomised controlled trial was conducted including 60 patients undergoing tonsillectomy with or without adenoidectomy. The patients were randomly assigned into two groups of 30 each: the topical haemocoagulase applied in the tonsillectomy procedure as Group A (n = 30) (interventional group) and patients undergoing tonsillectomy using a conventional saline pressure pack as Group B (n = 30) (control group). After obtaining informed and written consent from the study population, patients were categorised into Group A and Group B through randomisation. Outcome measures evaluated included operation time, intraoperative blood loss, slough formation and clearance rate, postoperative pain and feeding habits. Data analysis was performed using SPSS version 19, employing descriptive statistics, Shapiro-Wilk tests for normality, independent t-tests for normally distributed data and chi-square tests for categorical variables, with statistical significance set at p < 0.05.

Results revealed that Group A had significantly reduced operation times (p < 0.001), less intraoperative blood loss, faster slough clearance, and improved postoperative feeding habits compared to Group B.

The Topical haemocoagulase is a safe, effective and cost-efficient adjunct in tonsillectomy, offering significant advantages in surgical efficiency and postoperative recovery. Its ease of application and affordability make it a practical addition to routine surgical practice, benefiting both patients and healthcare providers. This study underscores the potential of haemocoagulase to enhance surgical outcomes and improve the overall quality of care in tonsillectomy procedures.