Related Experiment Video
Updated: Sep 19, 2025

05:07
CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
24.9K
Benefit of Topical Haemocoagulase Solution Application in Tonsillectomy: A Double-Blinded Study
Raadhika Shree1, Meenakshi Srinivasan1
1Department of Otorhinolaryngology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, SIMATS, Thandalam, Tamil Nadu, India.
Summary
Topical haemocoagulase significantly reduces tonsillectomy operation time and blood loss. This safe and effective treatment also improves postoperative healing and feeding habits, enhancing patient recovery.
Area of Science:
- Otolaryngology
- Surgical Innovation
- Hemostasis
Background:
- Tonsillectomy is a common surgical procedure with potential for blood loss and varied recovery times.
- Optimizing surgical efficiency and patient recovery are key goals in tonsillectomy.
Purpose of the Study:
- To evaluate the efficacy of topical haemocoagulase in reducing operation time and intraoperative blood loss during tonsillectomy.
- To assess the impact of topical haemocoagulase on postoperative healing, pain, and feeding habits.
Main Methods:
- A randomized controlled trial involving 60 patients undergoing tonsillectomy.
- Patients were assigned to receive either topical haemocoagulase (Group A) or a conventional saline pressure pack (Group B).
- Key outcomes measured included operation time, blood loss, slough formation/clearance, pain, and feeding habits.
Main Results:
- Topical haemocoagulase significantly decreased operation times (p < 0.001) and intraoperative blood loss.
- Faster slough clearance and improved postoperative feeding habits were observed in the haemocoagulase group.
- No adverse events related to haemocoagulase application were mentioned.
Conclusions:
- Topical haemocoagulase is a safe, effective, and cost-efficient adjunct for tonsillectomy.
- It offers significant advantages in surgical efficiency and postoperative recovery.
- Its ease of use and affordability make it a practical addition to routine surgical practice.

