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Resection of Midfacial Tumors Assisted by Virtual Planning Based on CT/MRI Multimodal Image Fusion: A Cohort Study
Lei-Hao Hu1, Wei Zhou1, Wen-Bo Zhang2
1Department of General Dentistry, Peking University School and Hospital of Stomatology and National Center for Stomatology and National Clinical Research Center for Oral Diseases and National Engineering Research Center of Oral Biomaterials and Digital Medical Devices and Beijing Key Laboratory of Digital Stomatology and NHC Key Laboratory of Digital Stomatology and NMPA Key Laboratory for Dental Materials, Haidian District, Beijing, 100081 People's Republic of China.
Objective:
This cohort study aimed to preliminarily explore the effect of midfacial tumor resection procedure with assistance of virtual planning based on CT/MRI multimodal image fusion.
Methods:
For the experimental cohort, patients with midfacial tumors receiving treatment from February 2019 to March 2021 were enrolled. Virtual planning was completed preoperatively based on CT/MRI multimodal image fusion. Tumor resection was performed under virtual planning-based surgical navigation, and intraoperative frozen sections were taken to determine resection margin status. For the control cohort, patients with midfacial tumors treated by the same surgical team were enrolled according to the same criteria. Patients underwent surgery assisted by virtual planning based on single-modality CT images. Resection margin and survival status were compared between groups during follow-up.
Results:
Altogether twenty-nine patients were enrolled. The resection margin status was significantly different between groups at the per-margin level (experimental group: 100% [66/66] negative; control group: 90.9% negative [70/77]; P = 0.014). During follow-up period, two patients in experimental cohort and seven patients in control cohort confirmed local recurrence.
Conclusions:
Patients with midfacial tumor who underwent virtual planning based on CT/MRI multimodal image fusion were more likely to have tumor-free resection margins. The use of the image fusion procedure may improve treatment outcomes in such patients.
Insights
Virtual planning using CT/MRI multimodal image fusion improved midfacial tumor resection margins. This advanced imaging technique enhances surgical outcomes and reduces local recurrence rates for patients.
Area of Science:
- Oncology
- Surgical Oncology
- Medical Imaging
Background:
- Midfacial tumors present complex surgical challenges.
- Accurate tumor resection is crucial for patient outcomes and survival.
- Current virtual planning methods may have limitations.
Purpose of the Study:
- To evaluate the preliminary effect of virtual planning using CT/MRI multimodal image fusion for midfacial tumor resection.
- To compare surgical outcomes between patients treated with multimodal image fusion versus single-modality imaging.
Main Methods:
- A cohort study comparing patients undergoing midfacial tumor resection with virtual planning based on CT/MRI multimodal image fusion (experimental) versus single-modality CT images (control).
- Preoperative virtual planning and intraoperative surgical navigation were utilized.
- Resection margin status and survival were assessed during follow-up.
Main Results:
- The experimental group achieved significantly better resection margin status (100% negative) compared to the control group (90.9% negative; P=0.014).
- Local recurrence rates were lower in the experimental cohort (2 patients) compared to the control cohort (7 patients).
Conclusions:
- Virtual planning based on CT/MRI multimodal image fusion is associated with a higher likelihood of achieving tumor-free resection margins in midfacial tumor surgery.
- This image fusion technique shows potential for improving treatment outcomes in patients with midfacial tumors.
