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Rapid SERS Analysis: From Laboratory to Real Sample
Haoyu Guo1,2, Shengfu Zhi1, Zeyu Zhao1,2
1State Key Laboratory of Marine Environmental Science, Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, Center for Marine Environmental Chemistry & Toxicology, College of the Environment and Ecology, Xiamen University, Xiamen 361102, China.
Abstract:
On the 50th anniversary of the discovery of surface-enhanced Raman spectroscopy (SERS), numerous reviews highlighted SERS advancements from different aspects, such as the historical evolution, enhancement mechanisms, quantitative analysis, and medical applications. However, how to develop the rapid SERS analysis for real samples has rarely been summarized yet. This review highlights the following three pivotal steps in this direction: (1) establishing reliable and highly selectively sensitive SERS analysis in the laboratory; (2) developing rapid sample pretreatment; and (3) AI-enhanced qualitative and quantitative SERS analysis.
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