Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy is an important non-invasive form of examination that plays a critical role in the diagnosis of rheumatic diseases accompanied by skin lesions. This technique is performed in real-time and can thus assist in determining the skin biopsy site. Skin lesions are common and important manifestations of most rheumatic diseases, including lupus erythematosus. In some rheumatic diseases, such as rheumatoid arthritis, the incidence of skin rashes may not be as high; however, those lesions that do develop can be diverse and deceptive, thereby complicating diagnosis. Dermoscopy and the observation of microscopic characteristics can assist in diagnosing primary diseases in their early stages. Herein, we present a protocol that provides a detailed overview of the standardized operation process of dermoscopy. Further, using discoid lupus erythematosus as an example, we demonstrate the important role of dermoscopy in the diagnosis of many different rheumatic diseases. Finally, we discuss the diverse dermoscopic manifestations of different rheumatic diseases and their associated skin lesions.