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Guiding ethical principles in transplant candidate selection committees: A scoping review protocol
Christopher H Kim1, Frank G Lee2, Tayyab S Diwan2
1Biomedical Ethics Research Program, Mayo Clinic, Rochester, Minnesota, United States of America.
Plos One
|June 2, 2025
Summary
This scoping review examines ethical principles in solid-organ transplant candidate selection. It highlights the need for improved fairness and reduced bias in selection processes to enhance public trust.
Area of Science:
- Medical Ethics
- Transplant Surgery
- Public Health Policy
Background:
- Ethical considerations are integral to all stages of organ transplantation, including recipient selection.
- Existing literature inadequately details the ethical insights guiding transplant candidate selection committees.
- Ethical frameworks could enhance equity in the organ allocation and recipient selection processes.
Purpose of the Study:
- To conduct a scoping review of published literature on ethical principles for solid-organ transplant candidate selection committees.
- To identify existing research on ethical decision-making in transplant candidate selection.
- To provide recommendations for improving ethical practices in selection committees.
Main Methods:
- Comprehensive literature search across PubMed, EMBASE, APA PsycInfo, SCOPUS, and CINAHL (1960-2024).
- Inclusion of full papers and abstracts in English focusing on transplant candidate selection.
- Two independent reviewers screened articles, with a third resolving conflicts; data extracted using Covidence.
Main Results:
- The review identified a paucity of studies specifically addressing the ethical principles guiding transplant candidate selection committees.
- Analysis revealed that the definition of a "right decision" in selection is not consistently elucidated.
- Systematic bias and discrimination in selection processes remain significant concerns.
Conclusions:
- There is a critical need to examine transplant candidate selection processes for potential biases and discrimination.
- Improving ethical frameworks and decision-making in selection can enhance fairness and equity.
- Addressing these issues is crucial for fostering public trust in organ transplantation.
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