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MSCD-VM-UNet: A Vision Mamba Combining Multi-Scale Global and Local Feature Extraction With Cross-Domain Feature
IEEE Journal of Biomedical and Health Informatics
|June 2, 2025
Summary
This study introduces MSCD-VM-UNet, an advanced medical image segmentation model. It improves accuracy by effectively integrating multi-scale features and enhancing boundary details for better diagnosis and treatment.
Area of Science:
- Medical Imaging
- Computer Vision
- Artificial Intelligence
Background:
- Accurate medical image segmentation is crucial for diagnosis and treatment planning.
- State Space Models (SSMs) offer linear complexity and long-range dependency modeling.
- Existing Mamba architectures struggle with multi-scale feature integration and boundary detail due to direct skip connections.
Purpose of the Study:
- To address limitations in current medical image segmentation models.
- To propose a novel architecture, MSCD-VM-UNet, for enhanced segmentation accuracy.
- To improve the integration of multi-scale features and handling of boundary details.
Main Methods:
- Developed the MSCD-VM-UNet architecture incorporating three novel modules.
- Implemented the Spatial Group Multi-Scale Attention Module (SGMAM) for multi-scale feature extraction and noise suppression.
- Integrated the Cross-Domain Feature Fusion Module (CDFFM) for frequency and spatial domain feature alignment.
- Utilized the Attention-Based Feature Injection Module (ABFIM) for adaptive feature fusion and weighting.
Main Results:
- The proposed modules significantly enhance the accuracy of the MSCD-VM-UNet architecture.
- MSCD-VM-UNet demonstrates superior performance in medical image segmentation tasks.
- The novel modules effectively capture multi-scale information and improve boundary detail handling.
Conclusions:
- MSCD-VM-UNet sets a new benchmark for medical image segmentation accuracy.
- The integration of SGMAM, CDFFM, and ABFIM modules overcomes limitations of previous architectures.
- This approach offers a robust solution for complex medical image segmentation challenges.

