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Related Experiment Videos

Massive ascites in systemic lupus erythematosus.

K W Wilkins, G S Hoffman

    The Journal of Rheumatology
    |June 1, 1985
    PubMed
    Summary

    Systemic lupus erythematosus can cause massive ascites, a fluid buildup in the abdomen. Corticosteroid treatment effectively resolved the ascites in this patient, with no recurrence after two years.

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    Area of Science:

    • Rheumatology
    • Internal Medicine
    • Gastroenterology

    Background:

    • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
    • Ascites, or abdominal fluid accumulation, is an uncommon but serious complication of SLE.

    Observation:

    • A 59-year-old woman presented with massive, painless ascites.
    • Comprehensive diagnostic workup, including exploratory laparotomy, excluded common causes like liver disease, kidney dysfunction, heart failure, infections, and malignancy.

    Findings:

    • The patient's ascites were definitively attributed to systemic lupus erythematosus.
    • Treatment with systemic corticosteroids led to a complete resolution of the ascites.

    Implications:

    • This case highlights the importance of considering SLE in the differential diagnosis of unexplained ascites, even in the absence of typical lupus symptoms.
    • Effective management of ascites in SLE patients can be achieved with immunosuppressive therapy, specifically corticosteroids.
    • Long-term remission of ascites is possible with appropriate treatment, as demonstrated by the two-year follow-up.

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