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Differentiating Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Responses Between Infection and Vaccination:
Sunav N Nayagam1, William Coote2,3, Matthew T C Carroll2
1School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
The Journal of Infectious Diseases
|June 3, 2025
Abstract:
Some common coronavirus disease 2019 (COVID-19) vaccines elicit antibody responses that most serological tests are unable to differentiate from an infection response. This presents a challenge for COVID-19 epidemiology and serosurveys. In this perspective, we examine the potential scale of this problem.
