Related Experiment Video
Updated: Oct 7, 2026

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
The Current Landscape for Human Papillomavirus Vaccination in Oropharyngeal Carcinoma
Nivedha Kumar1, James S Butler1, Jay Vashisht2
1Department of Radiation Oncology, Maimonides Medical Center/State University of New York University Downstate Medical Center, Brooklyn, NY.
Abstract:
Human papillomavirus is associated with the development of malignancies in the head and neck region, particularly oropharyngeal carcinoma. In recent years, there has been a significant increase in these virally mediated cancers, largely due to HPV strains 16 and 18. Existing literature supports a reduction in oral HPV infection following vaccination, and the FDA recently expanded the indication for the nonvalent Gardasil vaccine for use in HPV-related head and neck cancers in both men and women. The objectives of this paper are to review the evidence supporting the use of HPV vaccination in head and neck cancer, introduce HPV vaccinations currently being investigated in clinical trials, and assess barriers to production and widespread use of these vaccinations.
More Related Videos
06:57Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
07:43Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Published on: July 29, 2017
Related Concept Videos
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Treatment Resistent Cancers
Treatment Resistant Cancers
Cancer Prevention
Some...
Cancer Prevention
Some...
Tumor Immunotherapy