Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Self-Locking Screw01:16

Self-Locking Screw

2.9K
A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability.
A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed.
2.9K
Block Diagram Reduction01:22

Block Diagram Reduction

727
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
727
Controller Configurations01:22

Controller Configurations

484
Controller configurations are crucial in a car's cruise control system because they manage speed over time to maintain a consistent pace regardless of road conditions, thereby meeting design goals. In traditional control systems, fixed-configuration design involves predetermined controller placement. System performance modifications are known as compensation.
Control-system compensation involves various configurations, most commonly series or cascade compensation, in which the controller...
484
Bus Impedance Matrix01:24

Bus Impedance Matrix

622
Calculating subtransient fault currents for three-phase faults in an N-bus power system involves using the positive-sequence network. When a three-phase short circuit occurs at a specific bus, the analysis uses the superposition method to evaluate two separate circuits.
In the first circuit, all machine voltage sources are short-circuited, leaving only the prefault voltage source at the fault location. The positive-sequence bus impedance matrix can be determined by solving the nodal equations,...
622
Multimachine Stability01:25

Multimachine Stability

698
Multimachine stability analysis is crucial for understanding the dynamics and stability of power systems with multiple synchronous machines. The objective is to solve the swing equations for a network of M machines connected to an N-bus power system.
In analyzing the system, the nodal equations represent the relationship between bus voltages, machine voltages, and machine currents. The nodal equation is given by:
698
Self-Regulation01:25

Self-Regulation

359
Self-regulation, also known as self-control, encompasses a range of cognitive and behavioral processes that allow individuals to adjust their internal states and outward actions to align with socially acceptable norms and long-term goals. It plays a fundamental role in adaptive functioning, from resisting impulsive behaviors to persisting through challenging tasks. While its benefits are widely recognized, self-regulation is not limitless. Muraven and Baumeister's theory posits that...
359

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Peptide nanofibers and PAMP agonist combinations enhance pulmonary CD4 + T cell functionality of immune recall to vaccination.

Journal of nanobiotechnology·2026
Same author

Stereoselective Coassembly of Chiral Isomer Peptide Pairs.

ACS materials Au·2026
Same author

Peptide nanofibers and PAMP agonist combinations enhance pulmonary CD4<sup>+</sup>T cell functionality of immune recall to vaccination.

Journal of nanobiotechnology·2026
Same author

Substituent-Based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Substituent-based Modulation of Self-Assembly and Immunogenicity of Amphipathic Peptides.

bioRxiv : the preprint server for biology·2025
Same author

Protein structure and bioactivity upon adsorption and desorption from nanosilicate sustained release delivery devices.

Nanoscale·2025
Same journal

Application of Screen Printing in Perovskite Solar Devices.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

One-Shot Pd(II)-Catalyzed Multiple C-H Activation Enables Modular Construction of Fluorenylidene Oxindole-Based Multi(Polycyclic) Aromatic Enes.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Rapid Assembly of a Covalently Locked Organic Cage Revealing Symmetry-Matched Guest Recognition.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Expanding Cyanide-Bridged Weakly Coordinating Anions Through the Brominated Silver Salt Ag[BCNB<sup>Br</sup>].

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Photoexcited Nickel(0)-Catalyzed Direct Decarboxylative Cross-Coupling.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Divergent Total Syntheses of Bisnicalaterine Alkaloids Enabled by a Stereocontrolled Geissoschizol Synthesis.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
See all related articles

Related Experiment Video

Updated: May 1, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

13.0K

Modulating Peptide Self-Assembly via Triblock Chiral Patterning.

Conor L O'Neill1, Jonathan L Fascetti1, Zoe Clapacs1

  • 1Department of Biomedical Engineering, McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|June 3, 2025
PubMed
Summary
This summary is machine-generated.

Block heterochiral peptides, created by specific D-amino acid substitutions, exhibit unique self-assembly structures. This study explores chiral patterns in KFE12 peptides, revealing distinct morphologies based on their block structures.

Keywords:
chiralitypeptide self‐assemblysupramolecular morphology

More Related Videos

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.5K

Related Experiment Videos

Last Updated: May 1, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

13.0K
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

7.9K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

7.5K

Area of Science:

  • Supramolecular chemistry
  • Biomaterials science
  • Peptide self-assembly

Background:

  • Peptide self-assembly relies on cohesive interactions for hierarchical structure.
  • Chiral alterations, like D-amino acid substitution, significantly impact peptide assembly.
  • Block heterochiral peptides introduce chiral inversions within repeating motifs.

Purpose of the Study:

  • To combinatorially explore all triblock chiral patterns for the model β-sheet-forming peptide KFE12.
  • To investigate how different blockwise chiral arrangements influence peptide self-assembly morphology.
  • To understand the interplay between fundamental forces and chiral interfaces in peptide aggregation.

Main Methods:

  • Synthesis of KFE12 peptide variants with defined triblock chiral patterns.
  • Characterization of self-assembled morphologies using various analytical techniques.
  • Analysis of structural differences arising from enantiomeric chiral block arrangements.

Main Results:

  • Four distinct enantiomer pairs of triblock KFE12 peptides were generated.
  • Each enantiomer pair exhibited unique suprastructural morphologies.
  • Observed morphologies ranged from 4-nm fibrils to micron-scale aggregates.

Conclusions:

  • Blockwise chiral inversions in peptides dictate unique self-assembly outcomes.
  • Peptide morphology is sensitive to the spatial arrangement of intramolecular chiral interfaces.
  • This work highlights the tunable nature of peptide self-assembly through controlled chirality.