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Updated: Jun 14, 2025
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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Fissistonones A and B: Two Phenylpropanoyl Prenylated Naphthoquinones with Rearranged Carbon Skeletons from
Chu-Hua Lai1, Jun-Cheng Su2, Hai-Wang Yang1
1State Key Laboratory of Traditional Chinese Medicine Syndrome, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China.
Abstract:
Fissistonones A and B (1 and 2), two naphthoquinone derivatives with rearranged carbon skeletons, were obtained from the leaves of Fissistigma oldhamii. Structurally, compounds 1 and 2 featured an unprecedented phenylpropanoyl benzobicyclo[3.3.1]nonene core, which could be biosynthetically traced back to a planar naphthoquinone precursor via a cascade of intramolecular bond formation and ring cleavage. In addition, compounds 1 and 2 exhibited significant inhibitory activities on IL-8 production in the human keratinocyte HaCaT cell line.
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