[Research on software development and smart manufacturing platform incorporating near-infrared spectroscopy for measuring traditional Chinese medicine manufacturing process]
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View abstract on PubMed
Summary
This summary is machine-generated.Process analytical technology (PAT) using near-infrared (NIR) spectroscopy enhances traditional Chinese medicine (TCM) manufacturing. This integration ensures consistent product quality and drives TCM digitalization through smart platforms.
Area Of Science
- Analytical Chemistry
- Pharmaceutical Technology
- Digital Manufacturing
Background
- Process Analytical Technology (PAT) is crucial for modernizing traditional Chinese medicine (TCM) manufacturing.
- Ensuring consistent and controllable TCM product quality is a primary challenge in the industry.
- Near-infrared (NIR) spectroscopy has emerged as a key technology for real-time process monitoring.
Purpose Of The Study
- To systematically review the development and application of NIR spectroscopy combined with chemometrics in TCM manufacturing over two decades.
- To explore the use of accuracy profile (AP) validation methods in NIR spectroscopy practices.
- To analyze software development for NIR spectroscopy and its integration into smart factory platforms for TCM.
Main Methods
- Integration of NIR spectroscopy within a Process Analytical Technology (PAT) framework.
- Application of chemometrics for data analysis and model development.
- Development and implementation of a smart platform for TCM manufacturing processes.
- Utilizing accuracy profile (AP) for method validation.
Main Results
- NIR spectroscopy, integrated with PAT and chemometrics, has demonstrated significant advancements in TCM manufacturing over 20 years.
- The development of smart platforms incorporating NIR spectroscopy improves production efficiency and guarantees product quality.
- Software advancements and modeling technologies support the effective application of NIR spectroscopy.
- Accuracy profile (AP) validation provides a robust approach for NIR spectroscopy methods.
Conclusions
- The combination of NIR spectroscopy, chemometrics, and smart platforms offers substantial technical support for the digitalization and industrialization of TCM.
- Continued software development and smart manufacturing platform integration are vital for the future of TCM production.
- NIR spectroscopy plays a pivotal role in achieving consistent quality and enhanced efficiency in TCM manufacturing.
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