Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.1K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.1K
Human Genetics01:28

Human Genetics

743
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
743
Teratogenicity01:07

Teratogenicity

2.8K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.8K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

552
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
552
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

8.1K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhancing Prenatal Genetic Evaluation Through the Combination of Single-Gene Non-Invasive Prenatal Screening and Prenatal Imaging.

Prenatal diagnosis·2026
Same author

The role of anti-Müllerian hormone as a therapeutic agent to preserve the ovarian follicle pool during chemotherapy.

Journal of assisted reproduction and genetics·2026
Same author

Reproductive Carrier Screening Detects Early Actionable Metabolic Conditions.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

De Novo 2.2 Mb 19q13.42-q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model.

American journal of medical genetics. Part A·2026
Same author

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions.

Prenatal diagnosis·2026
Same author

Evaluating the Utility of RNAseq in Prenatal Diagnostics: Expression Profiles of Cultured Chorionic Villus and Amniotic Fluid Samples.

Prenatal diagnosis·2026
Same journal

Obstetric Care for Patients With Cognitive Disabilities.

Clinical obstetrics and gynecology·2026
Same journal

Dissecting the Americans With Disabilities Act (ADA) Requirements when Approaching Obstetric Patients With Disabilities: How to Ensure Your Spaces are Accessible for All.

Clinical obstetrics and gynecology·2026
Same journal

Clinician Comfort and Barriers to the Obstetric and Gynecologic Care of Patients With Disabilities.

Clinical obstetrics and gynecology·2026
Same journal

Obstetric Care for Patients With Visual Impairments: Preconception Counseling Through Postpartum Care.

Clinical obstetrics and gynecology·2026
Same journal

Menstrual Management and Contraception for Patients With Disabilities.

Clinical obstetrics and gynecology·2026
Same journal

Favoring Elective Hospitalization in Pregnancies With Vasa Previa.

Clinical obstetrics and gynecology·2026
See all related articles

Related Experiment Video

Updated: Sep 19, 2025

FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.0K

Prenatal Genetic Consultation and Testing.

Sarah Araji1, Lauren Westerfield2,3, Roni Zemet3,4

  • 1Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine.

Clinical Obstetrics and Gynecology
|June 4, 2025
PubMed
Summary
This summary is machine-generated.

Prenatal genetic testing advances enable precise diagnosis of fetal conditions. Accurate genetic information is crucial for guiding decisions on fetal therapy and management.

Keywords:
chromosomal microarray analysisfetal abnormalitiesfetal therapygenetic counselingnext-generation sequencingprenatal genetic testing

More Related Videos

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.2K
Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

9.5K

Related Experiment Videos

Last Updated: Sep 19, 2025

FISH for Pre-implantation Genetic Diagnosis
07:34

FISH for Pre-implantation Genetic Diagnosis

Published on: February 23, 2011

37.0K
Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
09:30

Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform

Published on: August 17, 2022

3.2K
Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

9.5K

Area of Science:

  • Medical Genetics
  • Prenatal Diagnosis
  • Fetal Medicine

Background:

  • Prenatal genetic testing has evolved significantly, offering more precise diagnostic capabilities.
  • Advanced technologies like chromosomal microarray analysis and exome sequencing expand the scope of detectable genetic conditions.

Purpose of the Study:

  • To review current prenatal genetic screening and testing methods.
  • To discuss indications for genetic testing and counseling strategies.
  • To explore genetic abnormalities linked to fetal structural anomalies and their impact on fetal intervention decisions.

Main Methods:

  • Review of existing literature on prenatal genetic tests.
  • Analysis of genetic abnormalities associated with fetal structural anomalies.
  • Examination of decision-making processes for fetal interventions.

Main Results:

  • Chromosomal microarray analysis and exome sequencing improve prenatal diagnosis accuracy.
  • Genetic diagnosis is essential for informed decisions regarding fetal therapy.
  • Specific genetic abnormalities correlate with fetal structural anomalies, influencing intervention choices.

Conclusions:

  • Enhanced prenatal genetic testing provides individualized diagnostic approaches.
  • Accurate genetic diagnosis is fundamental for guiding management and outcomes in cases eligible for fetal therapy.
  • Understanding genetic implications is key for effective decision-making in fetal interventions.