Related Experiment Video

Updated: Sep 19, 2025

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
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Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

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Impact of Anomalous Aortic Origin of Coronary Artery on Coronary Angiography: A Comparative Study

Arnaud Brochier1, Sofien Zayed1, Pierre Aubry2,3

  • 1North Site Cardiology Department, University Hospital of La Réunion, Saint-Denis, France.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|June 4, 2025
PubMed

Insights

Anomalous aortic origin of a coronary artery (AAOCA) significantly reduces coronary angiography success rates and increases procedural risks. This highlights the need for specialized training and optimized protocols for AAOCA patients.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Imaging

Background:

  • Anomalous aortic origin of a coronary artery (AAOCA) poses challenges in coronary angiography (CA), affecting procedural success.
  • While AAOCA prevalence and risks are known, its specific impact on CA outcomes remains unquantified.

Purpose of the Study:

  • To evaluate the impact of AAOCA on CA success and safety.
  • Focus on catheterization success rates, procedural quality, radiation exposure, and contrast media usage.

Main Methods:

  • Retrospective cohort study of 96 AAOCA patients and 96 matched controls (2011-2022).
  • Key endpoints: selective catheterization success, injection quality, fluoroscopy time, radiation dose, and contrast volume.
  • Statistical analysis using conditional logistic regressions and generalized estimating equations.

Main Results:

  • Significantly lower selective catheterization success in AAOCA+ group (28.1% vs. 90.6%).
  • AAOCA+ group had lower injection quality, longer fluoroscopy times, higher radiation exposure, and greater contrast usage.
  • All differences were statistically significant (p < 0.05).

Conclusions:

  • AAOCA significantly decreases diagnostic catheterization success rates.
  • AAOCA increases procedural risks including radiation exposure and contrast use.
  • Specialized training and optimized protocols are crucial for improving CA outcomes in AAOCA patients.
Abstract

Keywords:
anomalous aortic origin of coronary arteriescoronary angiographycoronary anomaliescoronary artery diseaseiodine contrast mediaradiation exposureselective catheterization

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