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Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases
Published on: August 23, 2024
Biologically synthesized metallic nanocarriers for efficient therapy of breast cancer
Saili Jagdale1, Rajkumar Samanta2,3, Mahavir Narwade1
1Department of Pharmaceutics, Poona College of Pharmacy, Bharati Vidyapeeth, Pune, India.
Introduction:
Breast cancer is one of the most common cancers in women and has a high mortality rate. Current treatment methods, including radiation, chemotherapy, and surgery, have limitations such as surrounding tissue damage and nonspecific toxicity, reducing their effectiveness. As a result, new therapeutic platforms are needed to enhance breast cancer treatment.
Areas Covered:
Nanoparticles, particularly metallic nanoparticles, have shown significant potential in overcoming the limitations of conventional treatments. These nanoparticles offer advantages such as high loading capacity, biocompatibility, adjustable size, and surface modification flexibility, making them ideal for drug delivery. This review focuses on the synthesis of metallic nanoparticles, emphasizing chemical and green synthesis methods. The green synthesis method has gained attention due to its eco-friendliness, biological safety, and cost-effectiveness. Research advancements in biosynthesized metallic nanoparticles for breast cancer therapy are discussed.
Expert Opinion:
The use of bio-synthesized magnetic nanoparticles in the treatment of breast cancer shows promise for both cytotoxicity and targeted medication delivery. By increasing anti-tumor immune responses, their optical and magnetic qualities improve immunotherapy's efficacy. Furthermore, It have the potential to provide potent anticancer treatments and stimulate multidisciplinary research to address current obstacles in the treatment of breast cancer, opening up new therapeutic development pathways.

