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Updated: Sep 19, 2025
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Copper(I)-catalyzed asymmetric addition of diarylphosphine sulfides to aldimines
Dong-Liang Xie1,2, Hu Tian1, Liang Yin1
1State Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
Abstract:
Herein, we report a copper(I)-catalyzed enantioselective addition of diarylphosphine sulfides to N-thiophosphinoyl aldimines. The reaction offers some advantages, such as mild conditions, an easy protocol, and high enantioselectivity. Control experiments indicate that the "soft-soft" interactions between the copper(I) catalyst and the sulfur atoms in both diarylphosphine sulfides and N-thiophosphinoyl aldimines facilitate the addition.
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