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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Paratonia in Advanced Dementia: A Frequently Misunderstood Movement Disorder.

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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Drivers with dementia: Forecasting the future.

Mark Rapoport1,2, Patrick A Byrne3, Kim Pho3

  • 1Department of Psychiatry, Termerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Journal of Alzheimer'S Disease : JAD
|June 4, 2025
PubMed
Summary
This summary is machine-generated.

The number of drivers with dementia in Ontario is projected to increase by over 200% by 2046. This study forecasts a significant rise in drivers with dementia, highlighting the need for public health and safety planning.

Keywords:
Alzheimer's diseaseautomobile drivingdementiaepidemiology

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Area of Science:

  • Gerontology
  • Neurology
  • Public Health

Background:

  • Driving skill decline is a known issue for individuals with dementia.
  • Accurate projections are needed to plan for future needs.

Purpose of the Study:

  • To estimate and forecast the number of drivers with dementia in Ontario, Canada.
  • To consider sex differences and driving cessation rates in dementia patients.

Main Methods:

  • Utilized historical provincial licensing data and population projections.
  • Incorporated dementia prevalence estimates from the Alzheimer's Society of Canada's Landmark study.
  • Conducted sensitivity analyses for sex differences and driving cessation assumptions.

Main Results:

  • Forecasted approximately 154,000 drivers with dementia in Ontario by 2046.
  • Estimated a 221% to 226% increase in drivers with dementia over two decades.
  • Modeled that females cease driving at twice the rate of males.

Conclusions:

  • Dementia prevalence is increasing, leading to a projected surge in drivers with dementia.
  • Highlights the need for enhanced health and public services for cognitively impaired drivers.
  • Emphasizes the importance of early detection of driving impairment and alternative transportation solutions.