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Natural killer cell function in children with severe malaria differs according to malaria transmission intensity

Grace Turyasingura, Kagan A Mellencamp, Ruth Namazzi

    Biorxiv : the Preprint Server for Biology
    |June 4, 2025
    PubMed
    Summary

    Severe malaria (SM) in children is linked to altered Natural Killer (NK) cell function, specifically reduced IFNγ production, irrespective of malaria transmission levels. This contrasts with memory-like NK cells previously associated with protection.

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