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  11. Prevalence Survey Of Antimicrobial Use Among Admitted Patients In Tertiary Care Hospital: An Observational Study.

Prevalence Survey of Antimicrobial Use among Admitted Patients in Tertiary Care hospital: An observational study.

S Aryal1, M Joshi1, B N Uprety1

  • 1Department of Pharmacology, Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.

Kathmandu University Medical Journal (KUMJ)
|June 4, 2025

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Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

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View abstract on PubMed

Summary
This summary is machine-generated.

Antimicrobial use was high in a Nepalese hospital, with 78.1% of inpatients receiving antibiotics. While adherence to essential medicines and generic prescribing was good, strengthening antimicrobial stewardship is crucial to combat resistance.

Area of Science:

  • Pharmacology
  • Infectious Diseases
  • Public Health

Background:

  • Antimicrobial resistance (AMR) is a significant global health threat.
  • Monitoring antimicrobial use is essential for AMR containment strategies.
  • Tertiary care hospitals play a critical role in antimicrobial prescribing patterns.

Purpose of the Study:

  • To assess antimicrobial utilization patterns in a tertiary care hospital in Lalitpur, Nepal.
  • To provide data for antimicrobial stewardship initiatives in the region.

Main Methods:

  • An observational, cross-sectional study using a modified World Health Organization point prevalence survey methodology.
  • Data collected from medical records of 324 inpatients at Patan Academy of Health Sciences.
  • Study conducted on September 25-26, 2023, focusing on acute care wards.

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Main Results:

  • Antibiotic usage was high at 78.1% among 324 inpatients.
  • Ceftriaxone was the most frequently prescribed antibiotic (30.1%).
  • High adherence to the National List of Essential Medicines (72.7%) and generic prescribing (91.7%) was observed.

Conclusions:

  • High antibiotic consumption necessitates enhanced antimicrobial stewardship programs.
  • While essential medicines and generic prescribing are positive, optimizing empirical use is vital.
  • Evidence-based practices are key to improving patient safety and combating antimicrobial resistance.