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Updated: Feb 22, 2026

Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis
Published on: July 11, 2019
Venturi effect simulating stenosis in hemodialysis arteriovenous fistulas
George Neves-Almeida1,2, Edna Maria de Faria Viana3, Marcos Rocha Vianna3
1Postgraduate Program in Health Sciences, FCMMG, Belo Horizonte, Minas Gerais, Brazil.
Background:
A collapse phenomenon associated with stenoses was observed during Doppler ultrasound (DUS) examinations in arteriovenous fistulas (AVFs).
Aim:
To investigate the influence of the phenomenon over the diagnosis of stenosis, its prevalence and cause.
Method:
Comparison of luminal diameters before and during downstream compression of the efferent vein (DCEV); retrospective cross-sectional analysis of the prevalence; and theoretical analysis based on cardiovascular physiology and flow mechanicals and analysis of pressure gradients.
Results:
DCEV increased the luminal diameter at the phenomenon sites from 1.64 ± 0.78 mm to 4.03 ± 1.42 mm (p < 0.0001). The prevalence of the phenomenon was 11.3% (25) between 221 different AVFs and 16.6% (25) between 150 AFVs with stenoses. Pressure gradients in systole (147.9 ± 67.15 mmHg) and diastole (66.74 ± 37.7 mmHg) indicated intraluminal low pressures at the phenomenon sites.
Conclusions:
The collapse phenomenon can simulate AVF stenoses ⩾50% in DUS examinations, have an important and high prevalence between AVFs with stenoses and is compatible with the Venturi effect.
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