Case Commentary: A herculean effort for Mycobacterium heraklionense-localized azithromycin bead pharmacokinetics

Non-tuberculous mycobacterial infections present significant treatment challenges due to resistance and limited data on optimal antibiotic regimens. A recently published case report provided an innovative approach to Mycobacterium heraklionese hand tenosynovitis with azithromycin-loaded calcium sulfate beads and valuable pharmacokinetic data with concentration measurements. This case demonstrates the ability of azithromycin-loaded calcium sulfate beads to achieve high local tissue concentrations with low systemic toxicity.