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Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report
Kazuaki Nishimura1,2, Seiji Kagami2, Haruka Kajio2
1Department of Obstetrics and Gynecology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Cancer Reports (Hoboken, N.J.)
|June 4, 2025
Summary
This study details a rare case of vulvar adenocarcinoma with pagetoid spread, where the primary cancer source remained unidentified. The findings highlight secondary extramammary Paget's disease in vulvar cancer.
Area of Science:
- Oncology
- Dermatopathology
Background:
- Pagetoid spread involves intraepithelial migration of cancer cells to the epidermis, mimicking Paget's disease.
- This phenomenon is rarely observed in vulvar adenocarcinoma.
- Identifying the primary tumor source can be challenging.
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