Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Condensins02:15

Condensins

3.7K
Condensins are large protein complexes that use ATP to fuel the assembly of chromosomes during mitosis. They transform the tangled, shapeless mass of post-interphase DNA into individualized chromosomes by compacting, organizing, and segregating chromosomal DNA.
The plant and animal cells contain two types of condensin complexes—condensin I and condensin II. Both complexes have five subunits: two SMC (Structural Maintenance of Chromosomes) subunits, a kleisin subunit, and two HEAT-repeat...
3.7K
Chemistry of the Cell02:58

Chemistry of the Cell

44.3K
The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity...
44.3K
Noncovalent Attractions in Biomolecules02:35

Noncovalent Attractions in Biomolecules

55.8K
Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
55.8K
Mechanisms of Membrane Domain Formation00:59

Mechanisms of Membrane Domain Formation

3.2K
Different physical properties of lipids and proteins allow them to localize and form distinct islands or domains in the membrane. Some membrane domains are formed due to protein-protein interactions, whereas others are formed due to the presence of specific lipids such as sphingolipids and sterols—for example, large proteins, such as bacteriorhodopsin, aggregate and create distinct domains.
Another mechanism for membrane domain formation involves membrane proteins interacting with...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oral lichen planus affecting the gingiva is associated with an increased incidence of aggressive periodontal pathogens: A comparative study.

Dental and medical problems·2026
Same author

Decoding heat through membrane nanoclusters in plants.

Journal of integrative plant biology·2026
Same author

Decoding the Salt-Tolerance Code of Green Revolution Cereals.

Molecular plant·2026
Same author

Infection cycles of viruses of the phylum Nucleocytoviricota.

Nature reviews. Microbiology·2026
Same author

Cellular water-potential sensing through biomolecular condensation.

Nature·2026
Same author

Redox-Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Related Experiment Video

Updated: Sep 19, 2025

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

915

Wet scissors: How biomolecular condensates cut cellular membranes.

Xiaofeng Fang1, Alexander I May2, Katharina Sporbeck3

  • 1School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Current Opinion in Plant Biology
|June 4, 2025
PubMed
Summary

Liquid-like biomolecular condensates use capillary forces to reshape cellular membranes and drive fission. This mechanism is key for cell division and membrane trafficking, offering new insights into intracellular organization.

More Related Videos

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

4.2K
Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.2K

Related Experiment Videos

Last Updated: Sep 19, 2025

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures
08:02

Author Spotlight: Developing Synthetic Cells from Programmable Amphiphilic DNA Nanostructures

Published on: May 31, 2024

915
Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
06:48

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

4.2K
Chemical Dimerization-Induced Protein Condensates on Telomeres
08:52

Chemical Dimerization-Induced Protein Condensates on Telomeres

Published on: April 12, 2021

3.2K

Area of Science:

  • Cell Biology
  • Biophysics

Background:

  • Cellular organization relies on membrane shape, with reshaping critical for processes like cell division and membrane trafficking.
  • Membrane fission, a key topological change, is often driven by specialized proteins forming oligomeric spirals.

Purpose of the Study:

  • To review evidence that capillary forces from biomolecular condensates can drive membrane reshaping and fission.
  • To describe the molecular and physical principles behind condensate-mediated membrane cutting.
  • To explore interactions between condensate-mediated and established membrane remodeling processes.

Main Methods:

  • Review of existing evidence on biomolecular condensates and membrane dynamics.
  • Analysis of recent findings on condensate involvement in multivesicular body formation.
  • Discussion of molecular and physical principles governing condensate-membrane interactions.

Main Results:

  • Biomolecular condensates, through capillary forces, can facilitate cellular membrane reshaping and drive fission events.
  • Condensates are implicated in multivesicular body formation, demonstrating their role in membrane remodeling.
  • Novel condensate-mediated fission processes may interact with established protein-driven mechanisms.

Conclusions:

  • Biomolecular condensates contribute significantly to membrane remodeling in the biogenesis of cellular structures.
  • Understanding condensate-mediated membrane reshaping can transform the study of intracellular organization and dynamics.
  • This mechanism offers a new perspective on how cells manage membrane dynamics.