Evaluating the relevant factors affecting the perioperative outcomes of laparoscopic fundoplication in 100 neurologically impaired patients: a multicenter retrospective joint study
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Updated: Jan 18, 2026

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Published on: September 22, 2023
Yoshinori Koga1, Koshiro Sugita2, Naoki Hashizume3
1Department of Pediatric Surgery, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, 830-0011, Japan. koga_yoshinori@med.kurume-u.ac.jp.
Background:
Postural features (e.g. scoliosis) make laparoscopic fundoplication more difficult in neurologically impaired patients (NIPs) than in non-NIPs [please check this carefully]. We therefore clarified the relevant factors associated with perioperative outcomes of NIPs.
Methods:
NIPs who underwent laparoscopic Nissen fundoplication were enrolled. We classified the patients according to age into < 18- and ≥ 18-year-old groups and evaluated the factors associated with perioperative outcomes. The endpoints were patient characteristics, acid-reflux index, operative time, blood loss, postoperative outcomes, and Endoscopic Surgical Skill Qualification System (ESSQS) certification.
Results:
One hundred and one patients underwent laparoscopic fundoplication. Blood loss and operative time were significantly higher in the ≥ 18-year-old group than in the < 18-year-old group. A multivariate regression analysis revealed that no factors were significantly associated with blood loss. However, a significant association was observed between the procedure performed by the ESSQS-certified pediatric surgeon and the operative time. In terms of postoperative outcomes, the length of hospital stay after operations performed or supervised by ESSQS-certified pediatric surgeons was significantly shorter than that after operations performed by pediatric surgeons without ESSQS certification.
Conclusion:
The involvement of pediatric surgeons with ESSQS certification was significantly associated with perioperative outcomes in NIPs during laparoscopic fundoplication, whereas physical characteristics and GER were not.
Levels Of Evidence:
Level III, case-control study.

